Applying single-molecule optical and AFM imaging and force-spectroscopy approaches, we search for to unravel the mechanistic facets of the construction and dynamics of chromosomes. Our research pursuits incorporate:
1996, first mesoscopic cost density waves products; and initial electrical measurements on one metallic nanocluster in between nanoelectrodes
Within the very same time, the group of Paul McEuen, who was then centered with the University of California, Berkeley, confirmed equivalent success on ropes of bundled nanotubes. Depending upon the wrapping angle, nanotubes can are available in metallic or semiconducting variants, a prediction that we and Charles Lieber’s team at Harvard University independently verified utilizing scanning tunnelling spectroscopy experiments.
Sculpting nano-electrodes by using a transmission electron beam for electrical and geometrical characterization of nanoparticles.
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Microbiology has only existed for a century, because we started to research micro-organisms a lot more significantly. I thought nanobiology was an suitable phrase, since all molecular biological pertinent interactions happen on the nanoscale: a protein is several nanometres in measurement, DNA is two nm thick.’
‘Initially we looked at Organic units using a Bodily view and acted on the basis on the instruments we realized. It took a few years just before we commenced Doing the job much more on the large Organic difficulties. I then began to contact it nanobiology, a phrase that did not exist at enough time.
Instance (one) of bending configurations in 3D simulations of DNA rods on nanopores. A part of the membrane is revealed in grey, the rim of your pore is highlighted in crimson, and a 3D rendering on the motion on the DNA rod is displayed.
‘Yes, I recognize people have been astonished at time. At the conclusion of the nineties, After i was in my forties, I was Professor of Molecular Electronics and I've to confess that it had become a little bit bored, I didn’t study A lot anymore. The sphere went much more into the appliance facet, how you can combine nanotubes into Digital circuits.
Resolving the phase dimension in condensin-driven DNA loop extrusion identifies ATP binding given that the stage-making method
An integrated microfluidic platform for quantifying drug permeation throughout biomimetic vesicle membranes
Lots of new phenomena have been found, and he and his investigate group established a number one position During this discipline of research. Dekker and his cees dekker exploration group learned new physics of nanotubes along with explored the feasibility of molecular electronics. In 1998, they have been the very first to develop a transistor according to only one nanotube molecule.
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‘I'm pushed by marvel and concerns. On a fabric stage I come across responses in physics, but I experience my deepest joy with God. That faith also drives my science And just how I manage people today.